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公開済みデータ一覧

Microarray

HaCaT keratinocytes
TGF-β3
(3 ng/ml, 1.5 h, 6 h, 24 h),
si-SMAD2/3, si-ETS1,
si-TFAP2A
GSE11710 Koinuma et al. (2009). Mol Cell Biol. 29, 172-86
TGF-β1
(5 ng/ml, 24 h),
Ras(G12V), Ras(N116Y),
si-p53
GSE60814 Vasilaki et al. (2016). Sci Signal. 9, ra84
HepG2
TGF-β3
(3 ng/ml, 1.5 h, 24 h),
si-HNF4α
GSE28798 Mizutani et al. (2011). J Biol Chem. 286, 29848-60
NCI-H441
TGF-β3
(3 ng/ml, 1.5 h, 24 h),
si-TTF1
GSE51510 Isogaya et al. (2014). Cell Res. 24, 994-1008.
OCUM-2MLN
dnTβRII GSE12336 Komuro et al. (2009). J Natl Cancer Inst. 101, 592-604.
NMuMG, including Exon Array
TGF-β1
(1 ng/ml, 24 h)
GSE28184 Horiguchi et al. (2012). Oncogene. 31, 3190-201.
Human umbilical vein endothelial cells (HUVEC)
BMP-6
(50 ng/ml, 2 h, 24 h)
BMP-9
(1 ng/ml, 2 h, 24 h)
GSE27661 Morikawa et al. (2011). Nucleic Acids Res. 39, 8712-8727.
Human pulmonary arterial smooth muscle cells (PASMC)
BMP-4
(50 ng/ml, 2 h, 24 h)
GSE27661 Morikawa et al. (2011). Nucleic Acids Res. 39, 8712-8727.

RNA-seq

HEK293T
si-ESRP2, si-Arkadia GSE60559 Mizutani et al. (2016). Oncogene. 35, 3514-23.
A549
TGF-β3
(2.5 ng/ml, 24 h),
sh-RBM47
GSE61910 Sakurai et al. (2016). Oncogene. 35, 5000-9.
TGF-β3
(1 ng/ml, 1.5 h, 24 h),
Ad-TTF1
GSE51510 Isogaya et al. (2014). Cell Res. 24, 994-1008.
OS-RC-2 (Human renal cell carcinoma)
si-ESRP2, si-Arkadia GSE66741 Mizutani et al. (2016). Oncogene. 35, 3514-23.
Mouse pancreatic endothelial cell line, MS-1
TGF-β2
(1 ng/ml, 72 h)
miRNA inhibitors
GSE70207 Katsura et al. (2016). Genes Cells. 21, 99-116.
EpH4/EpRas (normal mammary epithelial cells with/without oncogenic Ras)
TGF-β3
(1 ng/ml, 48 h),
si-Etv4 and si-Etv5
GSE69387 Arase et al. (2017). Sci Rep. 7, 1166.
TGS-01 and TGS-04 (patient-derived glioma-initiating cell lines)
BMP-4
(20 ng/ml, 24 h)
JGAS00000000077 Raja et al. (2017). Oncogene. in press.
Mouse embryonic stem cells (mESCs)
LIF+BMP-4
(10 ng/ml, 24 h)
GSE70581 Morikawa et al. (2016). Stem Cell Reports. 6, 64-73.

ChIP-chip, ChIP-seq

HaCaT keratinocytes
SMAD2/3 ChIP-chip GSE11710 Koinuma et al. (2009). Mol Cell Biol. 29, 172-86
LacZ, p63 ChIP-seq
TGF-β1/LacZ, p63 ChIP-seq
TGF-β1/Ras(G12V), p63 ChIP-seq
TGF-β1/Ras(N116Y), p63 ChIP-seq
GSE60814 Vasilaki et al. (2016) Sci Signal. 9, ra84
HepG2
SMAD2/3 ChIP-chip
HNF4α ChIP-seq
GSE28798 Mizutani et al. (2011). J Biol Chem. 286, 29848-60
Hep3B
SMAD2/3 ChIP-chip GSE28798 Mizutani et al. (2011). J Biol Chem. 286, 29848-60
A549
TGF-β3, SMAD3 ChIP-seq GSE51510 Isogaya et al. (2014). Cell Res. 24, 994-1008.
NCI-H441
TGF-β3/siCtrl, SMAD3 ChIP-seq
TGF-β3/siTTF1, SMAD3 ChIP-seq
TGF-β3/siCtrl, SMAD4 ChIP-seq
TGF-β3/siTTF1, SMAD4 ChIP-seq
TTF1 ChIP-seq
TGF-β3, TTF1 ChIP-seq
GSE51510 Isogaya et al. (2014). Cell Res. 24, 994-1008.
NCI-H345-TbRII
SMAD2/3 ChIP-seq** GSE63871 Murai et al. (2015). Cell Discov. 1, 15026.
EpH4/EpRas (normal mammary epithelial cells with/without oncogenic Ras)
Etv4 ChIP-seq
Etv5 ChIP-seq
GSE69387 Arase et al. (2017). Sci Rep. 7, 1166.
Human umbilical vein endothelial cells (HUVEC)
BMP-6, SMAD1/5 ChIP-seq
BMP-9, SMAD1/5 ChIP-seq
GSE27661 Morikawa et al. (2011). Nucleic Acids Res. 39, 8712-8727.
Human pulmonary arterial smooth muscle cells (PASMC)
BMP-4, SMAD1/5 ChIP-seq GSE27661 Morikawa et al. (2011). Nucleic Acids Res. 39, 8712-8727.
Mouse embryonic stem cells (mESCs)
naive/serum, Smad1/5 ChIP-seq
naive/BMP-4, Smad1/5 ChIP-seq
primed/BMP-4 1.5h, Smad1/5 ChIP-seq
primed/BMP-4 24h, Smad1/5 ChIP-seq
GSE70581 Morikawa et al. (2016). Stem Cell Reports. 6, 64-73.
* ChIP-seq data were re-analyzed and mapped to the latest version of the genome (hg38 or mm10).
** Peaks were called with the ChIP data alone, without control sample(s).

FAIRE-seq

EpH4/EpRas (normal mammary epithelial cells with/without oncogenic Ras)
TGF-β3
(1 ng/ml, 4 or 8 d),
si-Etv4 and si-Etv5
GSE69387 Arase et al. (2017). Sci Rep. 7, 1166.